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Compression Strength of Donor Bone for Posterior Lumbar Interbody Fusion Compression Strength of Donor Bone for Posterior Lumbar Interbody Fusion Forty-three blocks of allograft bone used clinically for posterior lumbar interbody fusion and twenty-three blocks of xenograft bone from goats and cows were tested in compression and compared with the clinical mechanical requirements of posterior lumbar interbody fusion. Variations in processing methods allowed evaluation of the effects of processing on mechanical strength. Fresh-frozen cancellus bone from Os Bone (Cleveland, OH) failed at an average load of 863 ± 615 N. Fresh-frozen cancellous bone from the Mid American Tissue Center (Massilon, OH) failed at an average load of 3492 ± 1720 N. Freeze-dried cancellus bone obtained from the American Red Cross failed at an average load of 1595 ± 1031 N. Air-dried ethylene oxide sterilized cancellus bone from Os Bone failed at an average load of 1338 ± 691 N. Air-dried ethylene oxide sterilized cancellous bone from Mid America failed at an average load of 1616 ± 1157 N. Fresh-frozen tricortical bone from Mid America failed at an average load of 2257 ± 1081 N. Air-dried ethylene oxide sterilized tricortical bone from Os Bone failed at an average load of 2474 ± 1928 N. Air-dried ethylene oxide sterilized tricortical bone from Mid America failed at an average load of 2308 ± 422 N. Bovine Surgibone from Unilab (Hillside, New Jersey) failed at an average load of 2967 ± 399 N. Strength of bone in compression was not weakened by freeze drying, air drying, ethylene oxide sterilization, or by incubation at 37°C for 1 week before testing. Four of nine blocks of fresh-frozen cancellous bone, seven of nineteen blocks of ethylene oxide sterilized cancellous bone and three of eighteen blocks of tricortical bone were of insufficient strength for unsupported use in interbody fusion. Radiographic density of the bone correlated with strength of bone in compression testing but did not provide a useful index of bone strength. Back to Papers and Presentations |
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